COVID-19

A “MMWR” report on mask wearing. Can the results be used for decision making?

A report from the CDC in MMWR (Morbidity and Mortality Weekly Report) on February 4, Volume 71, examined if wearing a mask protects from getting COVID-19. The study design is a case-control study. Cases were people who tested positive for COVID-19 and the comparison group was those who tested negative for COVID-19. These subjects were […]

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Wearing a mask for protection from COVID-19, a randomized trial.

Here is the Paper.  Here is a post on the potential problems with randomized trials. Commentary from editors at Annals of Internal Medicine regarding the paper.  I have been asked to post on the Danish study examining if wearing masks reduces the chance of getting COVID-19. This study has been discussed at length in commentaries

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How should randomized trials be done? The example of remdesivir for COVID-19

This week I POSTED comments regarding the NIH study on remdesivir for COVID-19. The post was spurred by a question from a person who was concerned about the study’s accuracy and worried that she may have to face a decision to accept the drug should she get ill. Several readers, after the post, asked how

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Should I accept Remdesivir if I get hospitalized from COVID-19?

Here is a paper.  Below is a summary of my critical appraisal of a study regarding a treatment for COVID-19. The patient asking the question is a sophisticated scientist who wanted my opinion regarding the NIH study on Remdesivir. She was not in a position to make a decision regarding treatment, but was concerned the

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